Avella International

• Malaria Treatment:
  • Artesunate is an antimalarial medication used for the treatment of uncomplicated malaria, particularly infections caused by Plasmodium falciparum.

• Pregnancy and Breastfeeding:

  • The use of artesunate during pregnancy is generally considered safe, especially in severe cases where the benefits outweigh the risks. However, medical supervision is crucial. It can be used during breastfeeding.

• Children:

  • Artesunate is considered safe and effective in children, but the dosage is adjusted based on weight and age. Pediatric dosing should be carefully calculated.

• Monitoring:

  • Regular monitoring of blood parameters, especially in severe cases, is important to assess the response to treatment and detect any potential side effects.

• Dosage Accuracy:

  • Administer the medication precisely according to the healthcare provider's prescription. Dosage adjustments may be necessary based on the patient's response.

• Adverse Reactions:

  • Serious adverse reactions are rare, but any signs of allergic reactions, severe vomiting, or other unexpected symptoms should be reported promptly to a healthcare provider.

• Drug Interactions:

  • Inform the healthcare provider about all medications being taken, including over-the-counter drugs and supplements, to avoid potential interactions.

Uses:

1. Metabolism Support: Catosal is often used to support the metabolism of animals, particularly during periods of stress, illness, or recovery.

2. Appetite Stimulation: It can be administered to stimulate appetite in animals with reduced food intake.

3. Recovery from Illness: Catosal may be included in the treatment plan for animals recovering from various diseases or conditions.

4. Performance Enhancement: In livestock and racehorses, Catosal may be used to enhance performance and reduce recovery time after strenuous activities.

Precautions:

1. Dosage and Administration: The dosage and administration should be determined by a veterinarian based on the specific needs and condition of the animal.

2. Injection Site Care: Proper injection site hygiene and technique should be followed to minimize the risk of injection site reactions.

3. Vitamin B12 Sensitivity: Some animals may be sensitive to vitamin B12, so caution should be exercised, especially in animals with known sensitivity.

4. Underlying Health Conditions: Catosal should be used with caution in animals with certain underlying health conditions. The overall health of the animal should be considered before administration.

5. Veterinary Supervision: Only licensed veterinarians or trained professionals should administer veterinary injections.

Side Effects:

1. Local Reactions: Injection site reactions, such as swelling, pain, or redness, may occur. These are usually mild and temporary.

2. Allergic Reactions: While rare, some animals may exhibit allergic reactions. Signs of an allergic reaction may include hives, facial swelling, or difficulty breathing. Seek immediate veterinary attention if these occur.

3. Overdose: Administering an incorrect dosage may lead to adverse effects. It's crucial to follow the prescribed dosage.

4. Gastrointestinal Upset: Some animals may experience mild gastrointestinal upset, including nausea or diarrhea.

Uses:

1. Cough Relief: Zedex-SF is primarily used to provide relief from dry and unproductive coughs.

2. Mucolytic Action: Guaifenesin, one of the active ingredients, is a mucolytic agent that helps in thinning and loosening mucus in the airways, making it easier to cough up.

3. Decongestant Action: Phenylephrine, another active ingredient, acts as a decongestant to relieve nasal congestion associated with coughs and colds.

Side Effects:

1. Drowsiness: Some individuals may experience drowsiness, although it's not a common side effect.

2. Nausea: Nausea or upset stomach may occur in some cases.

3. Dizziness: Dizziness is a possible side effect, and caution is advised, especially when performing activities that require alertness.

4. Headache: Headache is another potential side effect.

5. Dry Mouth or Throat: Guaifenesin may cause dry mouth or throat.

6. Allergic Reactions: While rare, allergic reactions such as rash, itching, or swelling may occur. Seek medical attention if you observe any signs of an allergic reaction.

Precautions:

1. Pregnancy and Breastfeeding: Consult with a healthcare professional before using Zedex-SF if you are pregnant or breastfeeding.

2. Medical Conditions: Inform your healthcare provider about any pre-existing medical conditions, especially hypertension, diabetes, or thyroid disorders.

3. Drug Interactions: Zedex-SF may interact with certain medications, including MAO inhibitors, tricyclic antidepressants, and beta-blockers. Inform your healthcare provider about all the medications you are taking.

4. Alcohol: Avoid consuming alcohol while taking Zedex-SF, as it may enhance the sedative effects.

5. Driving and Operating Machinery: Due to the potential for drowsiness and dizziness, it's advisable to avoid activities that require mental alertness until you know how the medication affects you.

6. Dosage: Follow the recommended dosage instructions provided by your healthcare provider or on the product label. Do not exceed the recommended dose.

7. Children and Elderly: Use caution when administering to children or the elderly, and follow age-appropriate dosing guidelines.

8. Storage: Store the syrup as per the instructions on the packaging, typically at room temperature away from light and moisture.

1. Atrial Fibrillation:

   • Eliquis is commonly prescribed to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (irregular heart rhythm).

2. Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE):

   • It is used for the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE).

3. Post-Orthopedic Surgery:

   • Eliquis may be used to prevent DVT and PE in patients who have undergone hip or knee replacement surgery.

1. Common Side Effects:

   • Bleeding (may be serious, and it can occur in various parts of the body)
   • Easy bruising
   • Nausea
   • Minor bleeding (e.g., nosebleeds)

2. Serious Side Effects:

   • Severe bleeding (gastrointestinal, intracranial, or other)
   • Allergic reactions (rare but can be severe)

1. Bleeding Risk:

   • Eliquis increases the risk of bleeding. It's crucial to monitor for signs of bleeding, and patients with a history of bleeding disorders should use Eliquis with caution.

2. Renal Impairment:

   • Eliquis is excreted through the kidneys, so caution is needed in patients with renal impairment. Dose adjustment may be necessary.

3. Liver Disease:

   • Patients with liver disease should be monitored closely, as the liver plays a role in Eliquis metabolism.

4. Drug Interactions:

   • Eliquis can interact with other medications, including certain antifungals, anticoagulants, and antiplatelet drugs. Inform your healthcare provider about all medications you are taking.

5. Pregnancy and Breastfeeding:

   • The use of Eliquis during pregnancy is generally avoided, especially in the first trimester. The safety of Eliquis during breastfeeding is not well-established.

6. Elderly Population:

   • Caution is advised in the elderly population, as they may have an increased risk of bleeding.

7. Spinal/Epidural Anesthesia or Puncture:

   • Eliquis increases the risk of bleeding during these procedures, and special precautions are required.

8. Discontinuation Before Surgery:

   • The decision to discontinue Eliquis before surgery should be made in consultation with a healthcare provider, as stopping anticoagulation increases the risk of thromboembolism.

9. Regular Monitoring:

   • Regular monitoring of renal function and other relevant parameters may be necessary, depending on the patient's individual health status.

Uses:

1. Insomnia: Zopiclone is primarily used to help people with insomnia by promoting sleep and improving sleep quality. It is often prescribed for short-term use, typically for no longer than two to four weeks, as it can be habit-forming if used for extended periods.

Precautions:

1. Prescription: Zopiclone is available only by prescription and should be taken under the guidance of a qualified healthcare provider. It is essential to use this medication as directed by your healthcare provider.

2. Short-term Use: Zopiclone is generally intended for short-term use to avoid the development of tolerance, dependence, and withdrawal symptoms. It is not suitable for long-term treatment of chronic insomnia.

3. Dosing: Take Zopiclone 7.5mg tablets as prescribed by your healthcare provider. Do not increase the dose without consulting your healthcare provider, as higher doses can increase the risk of side effects and dependency.

4. Tolerance and Dependence: Prolonged use of Zopiclone may lead to tolerance, meaning that over time, you may require higher doses to achieve the same effect. Additionally, abrupt discontinuation after prolonged use can lead to withdrawal symptoms, including rebound insomnia, anxiety, and restlessness.

5. Side Effects:

   Common side effects of Zopiclone 7.5mg tablets may include:

   • Bitter or metallic taste in the mouth
   • Dry mouth
   • Drowsiness or dizziness
   • Headache
   • Gastrointestinal symptoms (nausea, abdominal pain)

1. Consult a Healthcare Professional: The best source of information about any medication is your healthcare provider. They can provide personalized information based on your medical history and current health condition.

2. Package Insert or Medication Guide: Check the package insert or medication guide that comes with the medication. This document typically provides detailed information about the drug, including its uses, dosage, precautions, and potential side effects.

3. Online Medical Databases: You can search reputable online medical databases, pharmaceutical websites, or government health portals for information about the medication. These sources often provide detailed and up-to-date information.

4. Pharmacist: Your pharmacist is a valuable resource for information about medications. They can provide details on usage, potential side effects, and any precautions you should take.

Uses: Typbar TCV is used for the active immunization against typhoid fever in individuals aged six months and older. It helps the immune system recognize and defend against the bacteria that cause typhoid.

Precautions:

1. Pregnancy and Breastfeeding: The safety of Typbar TCV during pregnancy and breastfeeding is not well established. It is generally recommended to discuss with a healthcare professional if vaccination is needed in these situations.

2. Immunocompromised Individuals: The vaccine may have reduced efficacy in individuals with compromised immune systems. Consult with a healthcare provider if you have concerns about the immune status of the person receiving the vaccine.

3. Previous Allergic Reactions: Inform your healthcare provider if you or the person receiving the vaccine has a history of severe allergic reactions to any component of Typbar TCV or a previous dose of the vaccine.

Side Effects: Typically, vaccines may cause mild side effects that are temporary. Common side effects of Typbar TCV may include:

1. Pain, redness, or swelling at the injection site
2. Fever
3. Headache
4. Fatigue
5. Muscle pain

Serious side effects are rare but may include severe allergic reactions. Seek medical attention if you observe signs of a severe allergic reaction, such as difficulty breathing, swelling of the face or throat, or a rapid heartbeat.

Fluoxetine is FDA-approved for major depressive disorder (for patients eight years and older), obsessive-compulsive disorder, panic disorder, bulimia, binge eating disorder, premenstrual dysphoric disorder, and bipolar depression as well as treatment-resistant depression when used in combination with olanzapine.

Uses:

1. Nausea and Vomiting: Zofer injection, which contains the active ingredient ondansetron, is commonly used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery.

2. Postoperative Nausea and Vomiting (PONV): It is also used for the prevention and treatment of postoperative nausea and vomiting.

Side Effects:

Common side effects of ondansetron/Zofer injection may include:

1. Headache
2. Fatigue
3. Constipation
4. Dizziness
5. Flushing (feeling of warmth or redness in the face or neck)

Serious side effects are rare but can include:

1. Allergic Reactions: Symptoms may include rash, itching, swelling, severe dizziness, or difficulty breathing. Seek medical attention if you experience these symptoms.

2. Irregular Heartbeat: In rare cases, ondansetron may cause changes in heart rhythm. Inform your healthcare provider if you have a history of heart problems.

Precautions:

1. Allergies: Inform your healthcare provider of any known allergies to ondansetron or similar medications.

2. Liver Disease: If you have liver problems, discuss this with your healthcare provider, as dosage adjustments may be necessary.

3. Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The safety of ondansetron during pregnancy is not fully established, and your healthcare provider will assess the benefits and risks.

4. Medication Interactions: Ondansetron may interact with other medications, so inform your healthcare provider about all the medications you are taking, including prescription and over-the-counter drugs, as well as supplements.

5. Serotonin Syndrome: Ondansetron may rarely cause serotonin syndrome, particularly when combined with other medications that increase serotonin levels. Inform your healthcare provider if you experience symptoms such as agitation, hallucinations, rapid heartbeat, fever, muscle stiffness, or loss of coordination.

Uses: Fluorouracil is a topical medication commonly used to treat certain skin conditions. The 5% w/w ointment formulation is often prescribed for the following purposes:

1. Actinic Keratosis: Fluorouracil is used to treat precancerous lesions known as actinic keratosis, which are caused by sun exposure.

2. Superficial Basal Cell Carcinoma: It may be prescribed for the treatment of superficial basal cell carcinoma, a type of skin cancer.

Precautions:

1. Consultation with Healthcare Professional: Before using fluorouracil ointment, consult with a healthcare professional. They will assess your specific condition, medical history, and determine if fluorouracil is the appropriate treatment for you.

2. Skin Sensitivity: Expect skin reactions at the application site, including redness, swelling, peeling, and crusting. Some discomfort is common, but if you experience severe irritation or an allergic reaction, notify your healthcare provider.

3. Sun Protection: While using fluorouracil, protect the treated area from sunlight. Use sunscreen and wear protective clothing to prevent additional skin damage.

4. Pregnancy and Breastfeeding: Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. The safety of fluorouracil during pregnancy and breastfeeding is not well-established, and your healthcare provider will weigh the potential risks and benefits.

Side Effects: Common side effects of fluorouracil ointment may include:

1. Local Skin Reactions: Redness, inflammation, peeling, crusting, and discomfort at the application site.

2. Systemic Effects: Although rare, systemic absorption can occur, leading to side effects such as nausea, vomiting, diarrhea, and fatigue. This is more likely with prolonged use or application to large areas.

3. Allergic Reactions: Allergic reactions are possible, and if you experience symptoms like severe itching, rash, swelling, or difficulty breathing, seek medical attention immediately.

Uses:

1. Bacterial Infections: This medication is prescribed to treat a wide range of bacterial infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, sinusitis, otitis media, and certain dental infections.

2. Augmentin: Amoxicillin and Clavulanate Potassium is commonly sold under the brand name Augmentin.

Precautions:

1. Allergies: Before taking this medication, inform your healthcare provider of any allergies to penicillin or other antibiotics.

2. Medical History: Disclose your complete medical history, especially if you have a history of liver disease, kidney disease, or gastrointestinal problems.

3. Pregnancy and Breastfeeding: Discuss with your healthcare provider the use of this medication if you are pregnant or breastfeeding, as it is generally considered safe, but caution is advised.

4. Interactions: Inform your healthcare provider about any other medications or supplements you are taking, as Amoxicillin and Clavulanate Potassium can interact with other drugs.

5. Complete Course: It's essential to complete the full course of antibiotics, even if you start feeling better before the medication is finished. Stopping antibiotics prematurely can lead to antibiotic resistance.

Side Effects:

Common side effects of Amoxicillin and Clavulanate Potassium may include:

• Diarrhea
• Nausea
• Vomiting
• Abdominal pain
• Skin rash
• Headache

• Metastatic Breast Cancer:
  • Ebunat is primarily used in the treatment of metastatic breast cancer. It is often used in patients who have received at least two prior chemotherapy regimens for metastatic disease.

As with any medication, Ebunat may cause side effects. Common and serious side effects include:

1. Fatigue:

   • Tiredness and weakness are common side effects.

2. Nausea and Vomiting:

   • Gastrointestinal symptoms such as nausea and vomiting may occur.

3. Hair Loss:

   • Temporary hair loss (alopecia) is a common side effect.

4. Decreased Appetite:

   • Some individuals may experience a decrease in appetite.

5. Peripheral Neuropathy:

   • Numbness, tingling, or pain in the hands or feet (peripheral neuropathy) may occur.

1. Bone Marrow Suppression:

   • Eribulin can suppress bone marrow function, leading to a decrease in blood cell counts. This can increase the risk of infections, anemia, and bleeding.

2. Liver Dysfunction:

   • Liver function may be affected, and monitoring is important.

3. Cardiac Events:

   • Rarely, serious cardiac events may occur. Individuals with pre-existing heart conditions may be at higher risk.

1. Blood Cell Counts:

   • Regular monitoring of blood cell counts is crucial during treatment.

2. Liver Function:

   • Liver function tests should be performed regularly.

3. Peripheral Neuropathy:

   • Report any symptoms of peripheral neuropathy, such as numbness or tingling, to the healthcare provider.

4. Pregnancy and Breastfeeding:

   • Ebunat may cause harm to a developing fetus, so it is not recommended during pregnancy. Breastfeeding is also not recommended during treatment.

5. Previous Allergic Reactions:

   • Inform your healthcare provider if you have a history of allergic reactions to any medications.

6. Drug Interactions:

   • Inform your healthcare provider about all medications you are taking, including prescription, over-the-counter drugs, and supplements.

7. Cardiac Conditions:

   • Individuals with pre-existing cardiac conditions may require additional monitoring.

8. Renal Impairment:

   • Adjustments to the dosage may be necessary in individuals with renal impairment.

Uses:

1. Fertility Treatment: Zyhcg HP Injection is often used in fertility treatments, specifically in assisted reproductive technologies such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). It can help stimulate the release of mature eggs from the ovaries (ovulation) in women who have difficulty ovulating.

2. Hypogonadism: In some cases, hCG may be used in men with hypogonadism, a condition where the testes do not produce enough testosterone. hCG can stimulate the testes to produce more testosterone, which can help address symptoms associated with low testosterone levels.

3. Cryptorchidism: hCG may also be prescribed in cases of cryptorchidism, a condition where one or both testes fail to descend into the scrotum. It can stimulate testicular descent in prepubertal boys.

Precautions: Before using Zyhcg HP Injection, it's important to consider the following precautions:

1. Prescription Requirement: Zyhcg HP Injection is typically available by prescription only. It should be administered under the supervision of a healthcare provider who specializes in fertility or hormone-related issues.

2. Monitoring: Your healthcare provider will monitor your response to the medication, especially in fertility treatments. This may involve regular ultrasound scans and hormone level assessments.

3. Multiple Pregnancy: There is an increased risk of multiple pregnancies (e.g., twins or triplets) when using hCG in fertility treatments. Your healthcare provider will discuss this risk with you.

4. Ovarian Hyperstimulation Syndrome (OHSS): In fertility treatments, there is a risk of OHSS, a condition in which the ovaries become swollen and painful. This risk should be monitored closely by your healthcare provider.

Side Effects: Common side effects associated with Zyhcg HP Injection may include:

• Pain or swelling at the injection site
• Breast tenderness or enlargement
• Mood swings
• Bloating
• Mild pelvic pain
• Headache

Zyrop Injection, also known as Recombinant Human Erythropoietin Alfa, is a medication used to treat anemia associated with chronic kidney disease, chemotherapy-induced anemia, and anemia in certain HIV patients. Here is some information about its uses, side effects, and precautions:

Uses:

1. Anemia associated with chronic kidney disease: Zyrop Injection stimulates the production of red blood cells, which helps in managing anemia in patients with kidney disease.
2. Chemotherapy-induced anemia: It is used to treat anemia that occurs as a side effect of chemotherapy in cancer patients.
3. Anemia in HIV patients: Zyrop Injection can be prescribed to HIV patients who are taking certain medications that cause anemia.

Side effects:

1. Common side effects: These may include headache, joint pain, injection site reactions (such as redness, swelling, or itching), flu-like symptoms (fever, chills, muscle aches), and high blood pressure.
2. Serious side effects: In rare cases, Zyrop Injection can cause serious side effects such as allergic reactions (difficulty breathing, swelling of the face, lips, tongue, or throat), seizures, stroke, heart attack, blood clots, and worsening of high blood pressure.

Precautions:

1. Hypersensitivity: If you have a known allergy or hypersensitivity to erythropoietin or any other ingredients in Zyrop Injection, it is important to inform your healthcare provider before starting the treatment.
2. High blood pressure: Zyrop Injection may increase blood pressure. Inform your doctor if you have a history of high blood pressure or any other cardiovascular conditions.
3. Blood clots: There is a risk of blood clot formation with Zyrop Injection. Inform your doctor if you have a history of blood clots or if you are at an increased risk of developing blood clots.
4. Seizures: Zyrop Injection may trigger seizures in some individuals. If you have a history of seizures or epilepsy, discuss it with your doctor before starting the treatment.
5. Pregnancy and breastfeeding: The use of Zyrop Injection during pregnancy or breastfeeding should be discussed with a healthcare professional, as its safety in these situations is not well-established.

It's important to note that the above information is not exhaustive, and you should consult a healthcare professional or read the product information leaflet for complete and up-to-date information about Zyrop Injection, including dosage instructions, contraindications, and potential drug interactions.